a. baumannii — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T19717	Cyclo-L-Trp-L-Trp		Antifungal
	Cyclo-L-Trp-L-Trp is a broad-spectrum antifungal. It also induces a high degree of acetylation of histones.		Antifungal
T1569	Tigecycline	GAR-936	ribosome , Antibacterial , Antibiotic , Autophagy
	Tigecycline (GAR-936) is a broad-spectrum glycylcycline antibiotic derived from tetracycline. Tigecycline binds to the 30S ribosomal subunit, thereby interfering with the binding of aminoacyl-tRNA to the mRNA-ribosome co...		ribosome , Antibacterial , Antibiotic , Autophagy
T11125	Durlobactam sodium salt	ETX2514 sodium salt	Antibacterial
	Durlobactam sodium salt (ETX2514 sodium salt) is an inhibitor of β-lactamase with IC50 values of 4 nM, 14 nM, and 190 nM for Class A KPC-2, Class C AmpC, and Class D OXA-24, respectively. Durlobactam sodium salt can be u...		Antibacterial
T75279	Tigecycline tetramesylate
	Tigecycline tetramesylate (GAR-936 tetramesylate), a broad-spectrum glycylcycline antibiotic, exhibits a mean inhibitory concentration (MIC) for E. coli (MG1655 strain) of approximately 125 ng/mL [1]. For Acinetobacter b...
T70429	TP-6076
	TP-6076 is a fluorocycline antibiotic, inhibiting bacterial protein synthesis, exhibiting great antimicrobial activity against carbapenem-resistant A. baumannii.
T27211	DS-8587	DS 8587,DS8587,DS-8587 free
	DS-8587 is a DNA topoisomerase inhibitor. DS-8587 exhibits potent antibacterial activity against quinolone-resistant A. baumannii isolates that harbor mutations in quinolone resistance-determining regions. DS-8587 signif...
T80372	P1
	P1 is a broad-spectrum antimicrobial peptide exhibiting antibacterial activity against both Gram-positive and Gram-negative bacteria, including B. anthracis spores and Carbapenem-resistant strains of A. baumannii and K. ...
T68438	APO-6619
	APO-6619 is an iron chelator which was shown to inhibit growth of the following bacterial strains: Acinetobacter baumannii, Pseudomonas aeruginosa, Staphylococcus aureus, Klebsiella pneumoniae, and Escherichia coli. AP...
T74866	Antibacterial agent 116
	Antibacterial agent 116, a benzophenone-containing salicylanilide compound, exhibits potent antibacterial activity by inhibiting peptidoglycan formation. It is employed as a photoaffinity probe to label Acinetobacter bau...
T39296	DS86760016
	DS86760016 is a highly effective inhibitor of leucyl-tRNA synthetase (LeuRS), demonstrating potent activity against multidrug-resistant (MDR) Gram-negative bacteria including Escherichia coli, Klebsiella pneumoniae, and ...
T83758	SAAP 148 TFA	Synthetic Antimicrobial and Antibiofilm Peptide 148
	SAAP 148, an antimicrobial peptide, effectively combats various multidrug-resistant bacteria in vitro and, in vivo, reduces skin colony-forming units (CFUs) in mouse models of A. baumannii or methicillin-resistant S. aur...
T83689	Histatin 8 TFA	Hst-8
	Histatin 8, a salivary antimicrobial peptide derived from proteolytic fragments of histatin 3 and histatin 5, exhibits activity against A. baumannii strains, both colistin-susceptible and -resistant, at a concentration o...
T39983	SPR206 acetate
	SPR206 acetate is a polymyxin analog that exhibits antibiotic activity against Gram-negative pathogens, including multidrug-resistant (MDR) variants. By interacting with the outer membrane of the bacterium, SPR206 acetat...
T78673	Antibacterial agent 135
	Antibacterial Agent 135 (example 7) effectively inhibits various bacteria, including P. aeruginosa, A. baumannii, E. coli, and K. pneumoniae, with a minimum inhibitory concentration (MIC) greater than 64 μg/mL [1].
T70798	Benastatin B
	Benastatin B is a polyketide synthase-derived benastatin that has been found in Streptomyces and has diverse biological activities. It inhibits glutathione S-transferase (GST; Ki = 3.7 µM for the rat liver enzyme).2 Bena...
T83903	Polymyxin B2 sulfate
	Polymyxin B2, a significant component of polymyxin B, is an antibiotic cationic lipopeptide initially derived from B. polymyxa. This compound effectively inhibits P. aeruginosa, A. baumannii, K. pneumoniae, and E. cloaca...
T73798	Colistin
	Colistin (Polymyxin E), a polypeptide antibiotic with oral activity, exhibits strong efficacy against a range of Gram-negative rod-shaped bacteria, such as multidrug-resistant Pseudomonas aeruginosa, Acinetobacter bauman...
T79240	DNA gyrase B-IN-2
	DNA gyrase B-IN-2 (Compound E), a 2-aminobenzothiazole derivative, serves as a potent inhibitor of DNA gyrase B with substantial efficacy against ESKAPE pathogens. The compound exhibits potent nanomolar-range inhibition ...
T23460	Tigecycline mesylate		Others
	Tigecycline mesylate is a first-in-class, broad-spectrum antibiotic. It also has activity against antibiotic-resistant organisms.		Others
T23459	Tigecycline hydrochloride		Others
	Tigecycline hydrochloride is a first-in-class, broad-spectrum antibiotic. It also has activity against antibiotic-resistant organisms.		Others